Points of interest:
* Swallow whole Tablets with full glass of water.
* To reduce stomach upset, take Imuran tablets with food.
* Imuran may increase skin sensitivity to sun light, avoid excessive sun exposure and use high SPF sunscreen.
Side effects of Imuran:
* Leukopenia, thrombocytopenia.
* Fever.
* Nausea, vomiting, diarrhea.
Cautions:
* Monitor for toxicity weekly then every 3 months thereafter.
* Patients must immediately report any signs of infection, bruising, bleeding or any manifestation of bone marrow depression.
* Azathioprine is hepatotoxic and liver function tests should be routinely monitored.
* Patient should stop taking Imuran if jaundice becomes apparent.
* Caution is required in patients with renal or hepatic impairment.
* Infections such as chickenpox may become severe during treatment.
Interactions:
* ACE inhibitors: increased risk of anaemia when azathioprine is given with Enalapril or Captopril especially in renal impairment.
* Allopurinol: increases plasma levels and toxicity of azathioprine.
* Coumarins: the concomitant use reduces the anti-coagulant effect of coumarins.
Indications:
Imuran is used in the following cases:
* Organ transplantation (kidney, heart, liver): The adjuvant treatment in preventing the body's rejection of organ transplantation.
* Active rheumatoid arthritis.
Size :
100 Tabs
Made In: